Brilliant Breakthroughs Happen

Achieve your most ambitious research goals without
compromising your personal commitment to sustainability

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UV/Vis & NIR Spectrophotometry Systems

for best results & least waste

Do Not Aspire to Less.

UV/Vis & NIR Spectrophotometry Systems - Olis

From the small & affordable CPL Solo to the rapid-scanning CLARiTY 1000 to the ageless HP 8453, you can choose technologically excellent systems for your best results that reduce waste.

On this website, you will find spectrophotometry systems for UV/Vis and NIR absorbance, fluorescence, anisotropy, circular dichroism, and circularly polarized luminescence. And if you visit the CLARiTY section, you will discover a line of UV/Vis instruments for accurate absorbance measurements on turbid samples (whole cells, hydrogels, nanoparticles, juices and beer!), which allow you to reduce or eliminate consumable use in sample clarification.

In 1969, when our founder Dr. Richard J. DeSa published “A Practical Automatic Data Acquisition System for Stopped-flow Spectrophotometry,”( Computers and Biomedical Research), he had no thought of “upcycling” the spectrophotometer he was using nor did he anticipate that he would design endlessly upgradable spectrophotometers for hundreds of others to use. He was advancing his own ambitious research goals. But, by the early 1980s, he left his academic career to help you advance yours.

Hand-crafted, individually-produced, and supported with professional, personal attention, each OLIS product is designed to support your most ambitious research goals without compromising your personal commitment to sustainability.

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Clear Solutions

For purified and clarified samples, our cuvette models

Absorbance
Fluorescence
Kinetic

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Chiral Samples

For lanthanides to proteins, our CD & CPL models

Circular dichroism
Circularly Polarized
Luminescence

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Turbid Solids & Suspensions

For suspensions (nanoparticles to whole cells) our
CLARiTY models

Absorbance
Fluorescence
Kinetics

 Our company founder computerized (‘upcycled’) the spectrophotometers in his own laboratory in the 1960s and 70s. Today, you can choose to upcycle a spectrophotometer in your laboratory. Perennial favorites are the HP 8452, HP 8453, Cary 14, Cary 17, and Perkin-Elmer 983 IR.

You can also purchase an OLIS instrument which includes one of these timeless models.

For brand-new OLIS spectrophotometers that are designed on first principle to be endlessly upgradable, we cut the metal, wire the electronics, and mount the gratings right here in Athens, Georgia, USA.  

When you see numeric identifiers of 20, 45, 245, 620, and 1000, you are looking at brand-new OLIS absorbance, fluorescence, CD, and CPL models with designed-in upgradability.

Learn more about Circular Economy.

 

You are an expert in your field. You need correct results when your sample is ready. An OLIS spectrophotometer frequently becomes the proudest stopping point on the tour of your laboratory, because it achieves exactly what you need: best performance, minimal waste, and peace of mind.

 

 The Path Forward

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#1

You identify the instrument you need, upgraded or brand-new

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#2

We develop, produce or upcycle that spectrophotometry system

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#3

With the new system, achieve your most ambitious research goals without compromising your personal commitment to sustainability

You achieve a beginner’s mind by dropping all expectations and preconceived ideas—shutting off autopilot—and seeing things with an open mind and fresh eyes—like a beginner, like a child,

Beginner’s mind or Shoshin has proven to be a great tool for my professional, creative, and personal life. I stumbled upon this concept when I was learning to meditate.

Uv/Vis and NIR Spectrophotometry Systems

 At On-Line Instrument Systems, Inc. (“OLIS”), we produce and/or upcycle cutting-edge UV/Vis and NIR spectrophotometry systems for a wide variety of applications. These UV/Vis and NIR spectrophotometers are for absorbance, fluorescence, circular dichroism, and circularly polarized luminescence. The company also supports the widely respected HP 8453, Cary 14, Cary 17, and PerkinElmer 983 spectrometers, which are no longer supported by their original manufacturers yet remain top performance optically. 

OLIS spectrophotometry systems can be equipped with OLIS and third party accessories to meet the needs of a diverse range of researchers. Temperature control , titration, and mixing capabilities are among these optional enhancements.

Phosphorescence lifetime

Phosphorescence lifetime measurements are available in a free-standing system as well as add as an optional enhancement to the fluorescence and CPL models.

Chiral studies of ground and excited state molecules are supported for characterization of molecular chirality, providing valuable information about molecular structure and interactions.

Chiral studies of ground and excited state molecules are supported for characterization of molecular chirality, providing valuable information about molecular structure and interactions.

Fluorescence Spectroscopy

Fluorescence models are available for exceptional sensitivity and precision, enabling the accurate measurement of fluorescence emission and spectra.  Spectrofluorescence is used to in study the behavior of fluorophores and probing their interactions with other molecules.

NIR Spectroscopy

NIR studies are becoming increasingly important in fields such as pharmaceuticals, food science, and environmental analysis. OLIS NIR systems support the analysis of complex samples and the identification and quantification of various compounds. In addition to absorbance and fluorescence NIR systems, we also offer NIR CD and CPL spectrometers.

Circularly Polarized Luminescence

For researchers interested in circularly polarized luminescence, the OLIS CPL Solo the only commercial small and affordable model available. It offers highest sensitivity and precision in measuring chiral emissive molecules yielding valuable insights into molecular structure and interactions. Models for UV/Vis, Vis/NIR, NIR, and IR are available.

Anisotropy

Anisotropy measurements, which are useful for understanding the orientation and mobility of molecules, is available on all CPL and properly enhanced fluorescence systems. 

OLIS is committed to providing researchers with the most advanced and reliable UV/Vis and NIR spectrophotometry systems, supporting groundbreaking research and discoveries in a wide range of fields. Reducing waste in science is  very high priority for us, evidenced in both instrument longevity/ upgradability and reduced consumable use in sample preparation.

CLARiTY UV/Vis 

OLIS CLARiTY is a line of UV/Vis spectrophotometers for measuring pathlength correctable absorbance on light scattering (turbid/ hazy) samples as well as clear. 

CD UV/Vis

CD spectroscopy is used to study the chirality of molecules. OLIS produces CD spectrophotometers for deepest UV through NIR spectral ranges, all employing an entirely digital data acquisition method which can only result in the correct answer. 

Reflectance

Diffuse and specular reflectance can be added to several OLIS models. 

Modularity

OLIS spectrophotometers support a diverse range of capabilities, including numerous applications on a single optical bench, due to the highly modular nature of many models.  

Upcycled Spectrophotometry Systems  

All OLIS products have designed-in upgradability. And some of our most popular and successful products are produced from components of older instruments which are still outstanding for their optical performance.

This embrace of sustainable practices is baked into the history and future of OLIS.  Over the decades, hundreds of top quality. spectrophotometers including all OLIS models (OLIS RSM 1000, the OLIS DSM 1000 CD, the OLIS DM 45 fluorimeters, the OLIS DSM 172 CD & CPL, and the OLIS CLARiTY 245 UV/Vis, etc.) as well select classic HP, Cary, and PE models have been kept in top working condition and not relegated to the landfill.

By modernizing and upcycling spectrophotometers, OLIS extends the lifespan by double, triple, and longer, reducing waste and minimizing the environmental impact of scientific research.

Upcycled spectrophotometry systems are environmentally friendly, functionally excellent, and highly cost-effective. Researchers can access cutting-edge technology at roughly half the price. Affordability makes a top-tier instrument accessible to a wider range of laboratories, ultimately accelerating scientific discoveries and advancements in various fields.

OLIS spectrophotometry systems are revolutionizing the way researchers analyze light scattering samples and measure absorbance. For protein concentration, protein structures and interactions, and related studies using intact, whole cells rather than clarified subsets of them. 

ABOUT US

On-Line Instrument Systems is in Athens, Georgia and has been providing Uv/Vis and NIR Spectrophotometry Systems since its inception in the 1970s by Dr. Richard J. DeSa. With a vision of advancing the most challenging research goals without compromising a commitment to environmental responsibility.  We have consistently strived to deliver cutting-edge solutions backed by outstanding service and fair prices. 

As of January 2023, OLIS is now woman-owned and lead by Julie Ann DeSa Lorenz. 

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